This website section contains information about XL-S Medical product and clinical trial and weight loss in general. We created this section exclusively for Autralian Health Care Professionals, it has informational and educational purpose.By clicking on the “I agree” button, you are accepting the following terms:

  • You are a Health Care Professional.
  • The information provided is for professional educational use only and must not be used for any other purpose
  • This material does not substitute for, or replace, the advice of a qualified Health Care Professional.
  • All patients requirements are different. Each patient recommended XL-S Medical by a HCP should only be after a medical evaluation to confirm they are appropriate for this weight loss product.



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XL-S Medical has been clinically tested and the results have been published in “The Journal of Obesity” a highly esteemed medical journal. Click here to read the full trial.

Below is a summary of the key points of the study. LItramine is the active ingredient in XL-S Medical.

Study Title: A Natural Fiber Complex Reduces Body Weight in the Overweight and Obese: A double-Blind, Randomised, Placebo-Controlled Study

Reference: Grube et al. Obesity, 21: 58–64.

Study Objective: investigated the efficacy and safety of Litramine, a patented fibre complex

Method:  After a 2-week placebo run-in phase, subjects were randomized to receive either 3 g/day of Litramine or placebo. Subjects were encouraged to undertake physical activity, reduce diet plans by 500 kcal deficit/day and 30% energy from fat

Duration & study numbers: 125 patients randomised. 123 ITT over 12 weeks with 2 week run-in period

Inclusion Criteria: Obese and overweight (25 ≤BMI≤35) males and females, 18- 60 years. Women of childbearing age were included with their agreement to use appropriate birth control measures during the entire study duration.

Exclusion Criteria:

  • Known sensitivity to the ingredients
  • Presence of any GI disease,
  • History of eating disorder,
  • Taking anti-obesity drugs,
  • Use of medication that affects GI function,
  • Alcohol abuse,
  • Smoking cessation in the previous 6 months,
  • History of cardiac diseases, renal diseases,
  • Pregnant and lactating women

Primary Endpoint: Change in body weight (kg) at 12 weeks compared to baseline.

Secondary Endpoints:

  • Proportion of subjects lost at least 5 and 10% of baseline body weight;
  • Reduction in mean BMI;
  • Reduction in mean waist circumference,
  • Change in body fat content (kg and %)

Follow-up: Body weight was measured using a calibrated weighing scale. Subjects wore underwear and no shoes. They were followed up at baseline and at 4-week intervals, throughout the 12-week treatment period.

Key Results:

  • The mean body weight change from baseline was 3.8 ± 1.8 kg in IQ vs. 1.4 ± 2.6 kg in placebo (P<0.001).
  • More LItramine subjects lost at least 5% of their initial body weight compared to placebo (P< 0.027).
  • Litramine showed significantly greater reduction in BMI, body fat composition, and waist circumference compared with placebo
  • LItramine was well tolerated with no adverse reactions reported.




In this Roundtable report healthcare experts including a GP, Pharmacist, Dietitian, Psychologist and Nutritionist paint a picture of the challenges that both healthcare professionals and everyday Australian’s face when it comes to addressing the ‘overweight epidemic. Click here to down load the pdf.

Calculate your patients BMI to help you assess their weight status and the associated risk factors based on the results.

Claculate your patients BMI here


Below is some information that will help your patients understand the BMI calculation and what the number that is generated means. You can use the information below to help educate them and open up future dialogue about a weight loss and the benefits for their health and wellbeing.

What is BMI?

Body Mass Index (BMI) is widely used by doctors and health experts to determine whether a person is underweight, healthy or overweight. Because BMI looks at the relationship between your weight and height, it’s often a good indicator of how likely you are to suffer from health-related illnesses due to your weight now and in the future.

Generally experts classify people with a BMI of below 18.5 as underweight; 18.5 to 25 as healthy, 25 to 30 as overweight and over 30 as obese.



Underweight = BMI less than 18.5
Some people are naturally slim, but being underweight from poor nutrition or because of an illness could pose serious health risks. Tiredness, reduced immunity, anaemia, vitamin deficiencies and infertility are some of the illnesses associated with being underweight. People within this category shouldn’t start any weight loss programme.

Healthy weight = BMI 18.5 to 25
According to BMI guidelines, if a person’s BMI falls between 18.5 and 25 they are not at risk of weight-related diseases. To maintain a healthy weight, they should include plenty of fresh fruit, vegetables and enough vitamins and minerals in their daily diet.

Overweight = BMI 25 to 30
Carrying extra weight can put people at risk of heart disease, high blood pressure, diabetes, arthritis, infertility, asthma and cancer. Our free Support Programme is designed to help these people lose weight and live a balanced, more active lifestyle.

Obese = BMI over 30
According to BMI guidelines, a person with a BMI over 30 is classified as obese. People within this category are at an increased risk of heart disease, high blood pressure, diabetes, arthritis, infertility, asthma and cancer. We recommend persons in this category to consult a doctor or a healthcare professional before starting any weight loss programme

Starting a discuss with your patient about their increasing weight can be challenging for any doctor or healthcare professional.  It is a delicate subject and often has a significant amount of emotion attached to it from the patient’s perspective. You know that it is in their best interest to deal with their weight gain early, rather than waiting for their health to be impacted. It is much easier for patients to lose a small amount of weight than tackling it when it is a much larger issue.

The Primary Care Guidelines on the Management of Overweight and Obesity provide guidance on the best ways to have difficult conversations about a patient’s weight and the steps involved in working with them to develop a plan that works for them. Click here to view a copy of these summary guidelines.

Click here to download the full version of the Obesity Guidelines developed by the NHMRC.

Everyone loses weight at different rates. It is important to help your patients set realistic weight loss goals. Consistent regular weight loss helps them maintain their ideal weight long term. The National Heart Foundation has set out realistic weight loss goals.




It is important to highlight to patients that effective weight management requires long-term commitment, a healthy well-balanced diet and regular physical activity. Without this long-term focus they will be trapped in a yo-yo dieting pattern.

As an initial step, get them to understand roughly how many calories they are consuming in an average day and compare it to the normal recommended average calorie consumption.

  • Women – 2000 calories per day
  • Men- 2500 calories per day

XL-S Medical has shown through its clinical trial that taking XL-S Medical and consuming roughly 500 calories a day fewer than the recommended daily intake is effective in promoting weight loss. Incorporate some regular physical activity and they will burn through additional calories. By adopting a healthy lifestyle, eating healthy foods and keeping active they are giving themselves the best chance of success.

Provide your patients with a clear, easy to follow weight loss plan that they can incorporate into their daily schedule. Often patients need additional help to start them on their weight loss journey.

XL-S Medical is an effective clinically tested product which will assist your patients in achieving their weight loss goals. view clinical trial results here XL-S Medical should be part of a healthy diet and exercise plan. The XL-S Medical website provides them with information on healthy eating and exercise plans and a range of nutritional easy to prepare recipes.




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Use our free BMI calculator to determine your body mass index – and find out what it means.


Any questions about XL-S Medical? Find all answers to your questions in our FAQ section.


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